Zebrafish Protocols for Neurobehavioral Research 1st Edition by Allan Kalueff, Adam Michael Stewart ISBN 978-1617795978 1617795978

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Product details: 

ISBN 10: 1617795978

ISBN 13:  978-1617795978

Author: Allan V. Kalueff, Adam Michael Stewart

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research.  Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders.  Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

Table of contents: 

1. Adult Zebrafish Models

2. Measuring Effects of Psychostimulants on Egocentric Spatial Learning and Memory in Adult Zebrafish – By Rabia Nasir, Tenzin Choezom, Jennifer Cunningham, Benjamin Bajaj, Cristina Rubi, Jonathan Butler et al.

3. Cued Fear Conditioning in Zebrafish (Danio rerio) – By Masakazu Agetsuma, Tazu Aoki, Ryo Aoki, Hitoshi Okamoto

4. Assessing Learning and Memory Through the Active Avoidance Paradigm – By Xiaojuan Xu, Stefan Goetz

5. Assessing Habituation Phenotypes in Adult Zebrafish: Intra- and Inter-Trial Habituation in the Novel Tank Test – By Jolia Raymond, Simon Chanin, Adam Michael Stewart, Evan Kyzar, Siddharth Gaikwad, Andrew Roth et al.

6. Assessing Startle Responses and Their Habituation in Adult Zebrafish – By Simon Chanin, Caroline Fryar, Danielle Varga, Jolia Raymond, Evan Kyzar, Joseph Enriquez et al.

7. QTL Mapping Using Behavioral Traits in the Adult Zebrafish – By Dominic Wright

8. Assessing Epilepsy-Related Behavioral Phenotypes in Adult Zebrafish – By Daniel Desmond, Evan Kyzar, Siddharth Gaikwad, Jeremy Green, Russell Riehl, Andrew Roth et al.

9. Rapid Method for Acute Intracerebroventricular Injection in Adult Zebrafish – By Augusto Barbosa Júnior, Caio Maximino, Aparecida de Souza Fim Pereira, Carla Patricia Bejo Wolkers, Fabiana Luca Alves, Liliam Midori Ide et al.

10. Western Blotting Assay for Egr-1 Immediate Early Gene in Brain Tissue of Zebrafish Applied to Neuroethological Study – By Augusto Barbosa Júnior, Anette Hoffmann, Fabiana Luca Alves, Carla Patricia Bejo Wolkers, Fernando Massaru Hoshiko, Liliam Midori Ide et al.

11. Utilizing the Zebrafish Neurophenome Project (ZNP) Database for Analyses of Complex Neurophenotypes in Zebrafish Models

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Tags: Allan Kalueff, Adam Michael Stewart, Zebrafish Protocols, Neurobehavioral Research