Veterinary Immunology Principles and Practice Second Edition by Michael J. Day, Ronald D. Schultz – Ebook PDF Instant Download/Delivery: 978-1482224627, 1482224623
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Product details:
ISBN 10: 1482224623
ISBN 13: 978-1482224627
Author: Michael J. Day, Ronald D. Schultz
Veterinary Immunology: Principles and Practice has become the adopted text in numerous veterinary schools throughout the world. Widely updated with advances in knowledge since 2011, this second edition reflects the rapid development in the field.
The new edition presents expanded information on commonly used diagnostic test procedures and discusses newly arising diseases such as bovine neonatal pancytopenia. Maintaining the same reliable format as its predecessor, the book includes:
Learning objectives at the start of each chapter
Key points at the end of each chapter
17 clinical case studies demonstrating clinical context for the material covered in the chapters
Standard symbols in diagrams throughout the text to provide continuity
Clinical examples and clinicopathological figures throughout
A glossary of terms and list of commonly used abbreviations
Exploring the immunological concerns of both large animals and small, the book emphasizes immunological principles while applying them to the disease process and to clinical practice. It provides a practical textbook for veterinary students and a handy reference for practitioners.
Table of contents:
Chapter 1: An Overview of the Immune System
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Introduction
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History of Immunology
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The Immune System: An Overview
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The Evolution of the Immune System
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Key Points
Chapter 2: Antigens and Antibodies
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Introduction
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Antigens
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Antibodies
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Immunoglobulin Classes
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Antigen-Antibody Interaction
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Key Points
Chapter 3: The Complement System
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Introduction
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The Classical and Lectin Pathways
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The Alternative Pathway
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The Terminal Pathway
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Biological Consequences of Complement Activation
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Tests of Complement Function
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Key Points
Chapter 4: Serological Testing
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Introduction
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Serological Tests
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Key Points
Chapter 5: Cells and Tissues of the Immune System
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Introduction
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Primary Lymphoid Tissue
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Secondary Lymphoid Tissue
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Lymphocytes
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Distinguishing Between Immune Cells
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Lymphocyte Recirculation
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Mucosal Lymphocyte Recirculation
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Key Points
Chapter 6: The Major Histocompatibility Complex
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Introduction
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Graft Rejection
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Major Histocompatibility Antigens
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The Major Histocompatibility Complex
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The Inheritance of MHC
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MHC-Disease Associations
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Other Applications of Tissue Typing
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Key Points
Chapter 7: Antigen Presentation and Cytokines
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Introduction
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Antigen Presenting Cells
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Antigen Uptake
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Antigen Processing and Presentation
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Antigen Presenting by CD1 Molecules
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Antigen Presentation by B Cells and Non-Professional Antigen Presenting Cells
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Cytokines
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Key Points
Chapter 8: The Biology of T Lymphocytes
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Introduction
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The T-Cell Receptor
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T-Cell Development and Maturation
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T-Cell Activation
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The Role of CD4+ T Lymphocytes
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Cytotoxicity
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Memory Cells
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γδ Lymphocytes
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Natural Killer T Cells
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Key Points
Chapter 9: The Biology of B Lymphocytes
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Introduction
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Antigen Recognition by B Cells
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Development and Maturation of B Lymphocytes
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Activation of the B Lymphocyte
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B-Cell Receptor Diversity
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The Immunoglobulin Class Switch
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Affinity Maturation
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Kinetics of the Humoral Immune Response
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B1 and B2 Lymphocytes
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Memory B Lymphocytes
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Monoclonal Antibodies
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Key Points
Chapter 10: Testing of Cellular Immune Function
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Introduction
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Lymphocyte Stimulation Tests
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Tests of Cytotoxic Function
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Tests of Phagocytic Cell Function
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Key Points
Chapter 11: Immune Suppression
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Introduction
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Antigen Usage
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Antibody-Mediated Suppression
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Immunoregulatory Macrophages
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The Neuroendocrine-Immunological Loop
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Regulatory (Suppressor) T Lymphocytes
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Key Points
Chapter 12: Hypersensitivity Mechanisms
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Introduction
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The Gell and Coombs Classification of Hypersensitivity
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Type I Hypersensitivity
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Type II Hypersensitivity
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Type III Hypersensitivity
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Type IV Hypersensitivity
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Key Points
Chapter 13: The Immune Response to Infectious Agents
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Introduction
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The Immune Response to Viral Infection
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The Immune Response to Bacterial Infection
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The Immune Response to Helminth Infection
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The Immune Response to Protozoal Infection
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The Immune Response to Fungal Infection
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Key Points
Chapter 14: Cancer Immunology and Immune System Neoplasia
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Introduction
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Tumour Antigens
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The Antitumour Immune Response
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Tumour-Promoting Immune Activity
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Immunotherapy to Enhance the Antitumour Immune Response
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Tumours of the Immune System
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Key Points
Chapter 15: Immunological Tolerance
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Introduction
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Neonatal Tolerance
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Adult Tolerance
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Oral Tolerance
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Oral Tolerance as Immunotherapy
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Self-Tolerance
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Fetomaternal Tolerance
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Key Points
Chapter 16: Autoimmunity and Autoimmune Disease
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Introduction
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Autoimmune Disease
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The Genetic Basis for Autoimmunity
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Age Susceptibility to Autoimmune Disease
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Hormonal Influence on Autoimmunity
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Primary Versus Secondary Autoimmune Disease
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Immunodiagnostic Tests for Autoimmunity
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Key Points
Chapter 17: Allergy
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Introduction
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Factors Predisposing to Allergic Disease
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The Hygiene Hypothesis
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Allergic Disease in Animals
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Diagnosis of Allergic Disease
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Key Points
Chapter 18: Immune System Ontogeny and Neonatal Immunology
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Introduction
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Immune System Ontogeny
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Passive Transfer of Maternal Immune Protection
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Neonatal Vaccination
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Failure of Passive Transfer
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Primary Immunodeficiency
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Neonatal Isoerythrolysis
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Early Life Immune Development
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Key Points
Chapter 19: Immunodeficiency
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Introduction
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Primary Immunodeficiency
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Secondary Immunodeficiency
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Key Points
Chapter 20: Vaccination
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Introduction
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Passive Immunization
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Active Immunization
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Infectious Vaccines
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Non-Infectious Vaccines
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Vaccines Other Than for Infectious Disease
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Mucosal Vaccines
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Needle-Free Vaccination
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Future Vaccine Developments
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Basic Principles of Vaccination
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Vaccine Husbandry
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Adverse Consequences of Vaccination
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Key Points
Chapter 21: Immunotherapy
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Introduction
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Immunosuppressive Agents
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Janus Kinase Inhibitors
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Immunostimulatory Agents
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Allergen-Specific Immunotherapy
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Intravenous Immunoglobulin Therapy
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Recombinant Cytokine Therapy
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Cytokine Gene Therapy
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Monoclonal Antibody Therapy
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Antigen-Specific Immunotherapy
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Parasite Therapy
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Gene Therapy
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Stem Cell Therapy
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Adjunct Immunotherapy
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Key Points
Chapter 22: Case Studies in Clinical Immunology
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Introduction
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The Basis of Immune-Mediated Disease
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How Common Is Immune-Mediated Disease?
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Immunodiagnosis
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Case 1: Canine Immune-Mediated Haemolytic Anaemia
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Case 2: Canine Immune-Mediated Thrombocytopenia
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Case 3: Canine Systemic Lupus Erythematosus
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Case 4: Feline Blood Transfusion
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Case 5: Feline Multiple Myeloma
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Case 6: Equine Purpura Haemorrhagica
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Case 7: Bovine Thymic Lymphoma
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Case 8: Canine Atopic Dermatitis
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Case 9: Equine Severe Combined Immunodeficiency
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Case 10: Canine Lymphocytic Thyroiditis
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Case 11: Canine Immune-Mediated Polyarthritis
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Case 12: Bovine Allergic Rhinitis
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Case 13: Canine Drug Reaction
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Case 14: Canine Trapped Neutrophil Syndrome
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Case 15: Feline Lymphoid Leukaemia
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Case 16: Equine Neonatal Isoerythrolysis
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Case 17: Immunological Aspects of a Herd Outbreak of Bovine Viral Diarrhoea Virus Infection
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