Uterine Leiomyomas Pathogenesis and Management 1st Edition by Ivo Brosens 1842143077 9781842143070

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Product details:

ISBN 10 : 1842143077 

ISBN 13 : 9781842143070

Author:   Ivo Brosens 

This is an advanced clinical reference on the pathogenesis, clinical presentation, and treatment of uterine fibroids. The pathogenesis section focuses on the current understanding of the biological basis of fibroid development. The chapters on clinical aspects cover epidemiology, assessment and clinicopathological features. The main focus of the book is on the contemporary management of fibroids, which has undergone a revolution during the past decade with a better understanding of the impact on fertility and technical advances in endoscopic surgery, radiologic embolization and pharmaceutical alternatives such as GnRH-superagonists and progesterone intrauterine devices.

Uterine Leiomyomas Pathogenesis and Management 1st Table of contents:

I. Basic sciences
The epidemiology of uterine leiomyomata
Cytogenetic and other genetic insights into the pathogenesis of uterine leiomyomata
Regulation of smooth-muscle cell proliferation in leiomyomata
Gene expression and hormonal response
Angiogenesis and vascular responses in leiomyomata
Vascular structure of leiomyomata

II. Clinical
Clinical presentations and symptoms associated with uterine leiomyomata
Leiomyomata and reproductive function
Leiomyomata in pregnancy
Leiomyomata and sarcoma
Sonography of uterine leiomyomata
Magnetic resonance imaging of uterine leiomyomata
Office diagnosis of submucous leiomyomata

III. Therapeutic
Myomectomy
The hysteroscopic management of leiomyomata
Uterine leiomyomata: medical treatment
The cost effectiveness of treatments for uterine leiomyomata

IV. New developments
Uterine leiomyoma embolization
Laparoscopic occlusion of uterine vessels
High-intensity focused ultrasound
Asoprisnil, a selective progesterone receptor modulator (SPRM), for the management of symptomatic uterine leiomyomata

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Tags: Uterine Leiomyomas, Pathogenesis, Management, Ivo Brosens