Textbook of Clinical Trials Second Edition by David Machin, Simon Day, Sylvan Green ISBN 8126524945 978-8126524945
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ISBN 10: 8126524945
ISBN 13: 978-8126524945
Author: David Machin, Simon Day, Sylvan Green
This new edition retains its original aim to be a major work giving detailed coverage of trial methodology in each significant area of medicine. The book’s main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area. Specific examples are used throughout to address these issues. The field of clinical trials research is rapidly expanding and will continue to do so for the foreseeable future. This new edition ensures that the text remains firmly up to date. Table of Contents:List of ContributorsPreface to Second EditionPreface the First EditionIntroductionCancerCardiologyDentistry and Oral Health CareDermatologyInfectious DiseasesOphthalmologyPsychiatryReproductive HealthSurgery and AnesthesiaOther ProceduresSpecial PopulationsIndex
Table of contents:
Introduction
- The Development of Clinical Trials – Simon Day
- General Statistical Issues – David Machin
- The Cochrane Collaboration – Mike Clarke
Cancer
- Breast Cancer – Donald A. Berry, Terry L. Smith, and Aman U. Buzdar
- Childhood Cancer – Sharon B. Murphy and Jonathan J. Shuster
- Gastrointestinal Cancers – Daniel Sargent, Richard Goldberg, and Paul Limburg
- Melanoma – Ping-Yu Liu and Vernon K. Sondak
- Respiratory Cancers – Joan H. Schiller and Kyungmann Kim
- Adrenal Cortical Carcinoma – Isha Malik and Petros Perros
- Thyroid Cancer – Vijayaraman Arutchelvam and Petros Perros
- Urologic Cancers – Edith D. Canby-Hagino, Catherine M. Tangen, and Ian M. Thompson
- Haematologic Cancers: Challenges in Developing New Therapeutic Approaches – Charles A. Schiffer and Stephen L. George
Cardiology
- Acute Stroke – Philip Bath
- Cardiovascular Disease – Krishna Prasad
Dentistry and Oral Health Care
- Dentistry and Oral Health Care – May C.M. Wong, Colman McGrath, and Edward C.M. Lo
Dermatology
- Dermatology – Luigi Naldi and Cosetta Minelli
Infectious Diseases
- HIV Infection – Michael D. Hughes
- Infectious Diseases – Ingela Krantz
Ophthalmology
- Ophthalmology – Jonathan C.K. Clarke and Peng-Tee Khaw
Psychiatry
- Anxiety Disorders – M. Katherine Shear and Philip W. Lavori
- Cognitive Behaviour Therapy – Nicholas Tarrier and Til Wykes
- Psychotherapy for Depression – Graham Dunn
Reproductive Health
- Contraception – Gilda Piaggio and Timothy M.M. Farley
- Gynaecology and Infertility – Siladitya Bhattacharya and Jill Mollison
- Early Pregnancy Termination – Beverly Winikoff and Batya Elul
- Maternal and Perinatal Health – José Villar, Allan Donner, Edgardo Abalos, and Liana Campódonico
Respiratory
- Respiratory Medicine – Anders Källén
Surgery & Anaesthesia
- Anaesthesia and Pain – Paul S. Myles and John Rigg
- General Surgery – Dr. Olga Jonasson and Domenic Reda
- Plastic Surgery – Reconstructive Surgery – Erik Ang and Woffles Wu
- Plastic Surgery – Aesthetic Surgery – Woffles Wu and Erik Ang
Transplantation
- Renal Transplantation – Vathsala Anantharaman
Other Procedures
- Wound Healing – Colin Song and Edwin Chan
- Palliative Care – Robert S. Krouse and David Casarett
- Complementary Medicine – Ping-Chung Leung
- Cluster Randomized Trials in Health Care Research – Randall D. Cebul, Neal V. Dawson, and Thomas E. Love
- Nursing – Nicola Crichton
Special Populations
- Clinical Trials in Paediatrics – Johan P.E. Karlberg
- Clinical Trials Involving Older People – Carol Jagger and Antony J. Arthur
- Clinical Trials in Rare Diseases – Simon Day
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