Progress in Heterocyclic Chemistry Volume 27 1st Edition by Gordon Gribble, John Joule ISBN 978-0081000243 0081000243

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ISBN 10:  0081000243

ISBN 13: 978-0081000243

Author: Gordon Gribble, John A. Joule

Progress in Heterocyclic Chemistry (PHC), Volume 27, is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists.

The highlight chapters in Volume 27 are all written by leading researchers and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2014. Additional articles in this volume are “The Use of Propargyl Vinyl Ethers in Heterocycle Synthesis” and “Recent Progress of Phosphonium Coupling in Heterocyclic and Medicinal Chemistry.”

As with previous volumes in the series, Volume 27 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

Recognized as the premiere review of heterocyclic chemistry
Includes contributions from leading researchers in the field
Provides a systematic survey of the important 2014 heterocyclic chemistry literature
Includes articles on new developing topics of interest to heterocyclic chemists

Table of contents: 

• Foreword
• Editorial Advisory Board Members Progress in Heterocyclic Chemistry
• Chapter 1. Propargyl Vinyl Ethers as Powerful Starting Points for Heterocycle Synthesis
  • 1.1. Introduction
  • 1.2. Synthesis of Furans and Pyrroles via Propargyl Claisen Rearrangement
  • 1.3. Synthesis of 1,3-Oxazolidines via Microwave Synthesis
  • 1.4. Synthesis of 2H-Pyrans and 1,2-Dihydropyridines
  • 1.5. Summary
• Chapter 2. Recent Progress of Phosphonium Coupling in Heterocyclic and Medicinal Chemistry
  • 2.1. Introduction
  • 2.2. Discovery of Phosphonium Coupling
  • 2.3. Phosphonium Coupling for Direct Amination
  • 2.4. Phosphonium Coupling for Direct Etherification
  • 2.5. Phosphonium Coupling for Direct Thioetherification
  • 2.6. Phosphonium Coupling for Direct Alkylation
  • 2.7. Phosphonium Coupling for Direct Arylation
  • 2.8. Phosphonium Coupling for Direct Alkynylation
  • 2.9. Phosphonium Coupling for Nucleoside Chemistry
  • 2.10. Summary
• Chapter 3. Three-Membered Ring Systems
  • 3.1. Introduction
  • 3.2. Epoxides
  • 3.3. Aziridines
• Chapter 4. Four-Membered Ring Systems
  • 4.1. Introduction
  • 4.2. Azetidines, Azetines, and Related Systems
  • 4.3. Monocyclic 2-Azetidinones (β-Lactams)
  • 4.4. Fused and Spirocyclic β-Lactams
  • 4.5. Oxetanes, Dioxetanes, and 2-Oxetanones (β-Lactones)
  • 4.6. Thietanes and Related Systems
  • 4.7. Silicon and Phosphorus Heterocycles: Miscellaneous
• Chapter 5.1. Five-Membered Ring Systems: Thiophenes and Se/Te Derivatives
  • 5.1.1. Introduction
  • 5.1.2. Synthesis of Thiophenes, Selenophenes, and Tellurophenes
  • 5.1.3. Elaboration of Thiophenes and Benzothiophenes
  • 5.1.4. Synthesis of Thiophenes, Selenophenes, and Tellurophenes for the Use in the Material Sciences
  • 5.1.5. Thiophene, Selenophene, and Tellurophene Derivatives in Medicinal and Environmental Chemistry
• Chapter 5.2. Five-Membered Ring Systems: Pyrroles and Benzo Analogs
  • 5.2.1. Introduction
  • 5.2.2. Synthesis of Pyrroles
  • 5.2.3. Reactions of Pyrroles
  • 5.2.4. Synthesis of Indoles
  • 5.2.5. Reactions of Indoles
  • 5.2.6. Isatins, Oxindoles, Indoxyls, and Spirooxindoles
  • 5.2.7. Carbazoles
  • 5.2.8. Azaindoles
  • 5.2.9. Isoindoles
• Chapter 5.3. Five-Membered Ring Systems: Furans and Benzofurans
  • 5.3.1. Introduction
  • 5.3.2. Reactions
  • 5.3.3. Synthesis
• Chapter 5.4. Five-Membered Ring Systems: With More than One N Atom
  • 5.4.1. Introduction
  • 5.4.2. Pyrazoles and Ring-Fused Derivatives
  • 5.4.3. Imidazoles and Ring-Fused Derivatives
  • 5.4.4. 1,2,3-Triazoles and Ring-Fused Derivatives
  • 5.4.5. 1,2,4-Triazoles and Ring-Fused Derivatives
  • 5.4.6. Tetrazoles and Ring-Fused Derivatives
• Chapter 5.5. Five-Membered Ring Systems: With N and S Atom
  • 5.5.1. Introduction
  • 5.5.2. Thiazoles
  • 5.5.3. Isothiazoles
• Chapter 5.6. Five-Membered Ring Systems: With O and S (Se, Te) Atoms
  • 5.6.1. 1,3-Dioxoles and Dioxolanes
  • 5.6.2. 1,3-Dithioles and Dithiolanes
  • 5.6.3. 1,3-Oxathioles and Oxathiolanes
  • 5.6.4. 1,2-Dioxolanes
  • 5.6.5. 1,2-Dithioles and Dithiolanes
  • 5.6.6. 1,2-Oxaselenolanes
  • 5.6.7. Three Heteroatoms
• Chapter 5.7. Five-Membered Ring Systems: With O and N Atoms
  • 5.7.1. Isoxazoles
  • 5.7.2. Isoxazolines
  • 5.7.3. Isoxazolidines
  • 5.7.4. Oxazoles
  • 5.7.5. Oxazolines
  • 5.7.6. Oxazolidines
  • 5.7.7. Oxadiazoles
• Chapter 6.1. Six-Membered Ring Systems: Pyridine and Benzo Derivatives
  • 6.1.1. Introduction
  • 6.1.2. Overview of Pyridine and (Iso)quinoline Uses
  • 6.1.3. Synthesis of Pyridines
  • 6.1.4. Reactions of Pyridines
  • 6.1.5. Synthesis of Isoquinolines
  • 6.1.6. Reactions of Isoquinolines
• Chapter 6.2. Six-Membered Ring Systems: Diazines and Benzo Derivatives
  • 6.2.1. Introduction
  • 6.2.2. Pyridazines and Benzo Derivatives
  • 6.2.3. Pyrimidines and Benzo Derivatives
  • 6.2.4. Pyrazines and Its Benzo Derivatives
• Chapter 6.3. Triazines and Tetrazines
  • 6.3.1. Triazines
  • 6.3.2. Tetrazines
• Chapter 6.4. Six-Membered Ring Systems: With O and/or S Atoms
  • 6.4.1. Introduction
  • 6.4.2. Heterocycles Containing One Oxygen Atom
  • 6.4.3. Heterocycles Containing One or Two Sulfur Atoms
  • 6.4.4. Heterocycles Containing Two or More Oxygen Atoms
  • 6.4.5. Heterocycles Containing Both Oxygen and Sulfur in the Same Ring
• Chapter 7. Seven-Membered Rings
  • 7.1. Introduction
  • 7.2. Seven-Membered Systems Containing One Heteroatom
  • 7.3. Seven-Membered Systems Containing Two Heteroatoms
  • 7.4. Seven-Membered Systems Containing Three or More Heteroatoms
  • 7.5. Future Directions
• Chapter 8. Eight-Membered and Larger Rings
  • 8.1. Introduction
  • 8.2. Carbon–Oxygen Rings
  • 8.3. Carbon–Nitrogen Rings
  • 8.4. Carbon–Sulfur Rings
  • 8.5. (Carbon–Nitrogen)–(Carbon–Oxygen) Rings
  • 8.6. Carbon–Nitrogen–Oxygen Rings
  • 8.7. Carbon–Nitrogen–Sulfur/Selenium Rings
  • 8.8. Carbon–Oxygen–Sulfur Rings
  • 8.9. Carbon–Nitrogen–Metal Rings
• Index

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