Omic Studies of Neurodegenerative Disease Part B 1st Edition by Michael Hurley ISBN 0128047623 978-0128047620

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Product details:

ISBN 10: 0128047623
ISBN 13: 978-0128047620
Author: Michael Hurley

Omic Studies of Neurodegenerative Disease: Part B is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields.

The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.

• Provides the expertise of leading contributors in the field
• Demonstrates how findings in the fields of genomics, proteomics, and metabolomic studies can combined for further insights
• Informs the reader on the current state of the studies used to study the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research

Omic Studies of Neurodegenerative Disease Part B 1st Table of contents:

Chapter One: Utility of Autoantibodies as Biomarkers for Diagnosis and Staging of Neurodegenerative Diseases

Abstract

1 Introduction: A Brief History of Autoantibodies

2 A Causal Role for Autoantibodies Revealed in Well-Known Autoimmune Diseases

3 Autoantibodies in Cancer: Byproduct or Biomarker?

4 Escalating Involvement of Autoantibodies in Neurological and Neurocognitive Disorders

5 Autoantibodies: Abundant, Ubiquitous, and Clinically Useful

6 Methods of Autoantibody Detection in Biofluids

7 Utility of Autoantibodies as Biomarkers of Disease

8 Conclusions and Perspectives

Acknowledgments

Chapter Two: Metabolomics of Neurodegenerative Diseases

Abstract

1 Metabolomics in Medicine

2 Metabolomics Biomarkers of Disease

3 Metabolomics Biomarker Discovery in Neurodegenerative Disorders

4 Summary

Acknowledgments

Chapter Three: Parkinson’s Disease: In Vivo Brain Metabolomics by MRS

Abstract

1 Proton MRS

2 1H MRS: Compounds Detectable In Vivo

3 Phosphorus MRS

4 Mitochondrial Dysfunction

5 Other Findings

6 High Magnetic Field

7 Parkinson’s Disease and Solvent Exposure

8 Conclusions

Chapter Four: Recent Advances and Applications of Metabolomics to Investigate Neurodegenerative Diseases

Abstract

1 Introduction

2 Metabolomics and Neurodegenerative Disorders

3 Conclusions

Chapter Five: Lipidomics of Human Brain Aging and Alzheimer’s Disease Pathology

Abstract

1 Introduction

2 Lipidomics of Human Brain

3 Lipidomics of Human Brain Aging

4 Lipidomics of Alzheimer’s Disease Pathology

5 Summary and Future Prospects

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Tags: Michael Hurley, Omic Studies, Neurodegenerative Disease