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(Ebook PDF) Immunology and Diseases of the Gut 1st Edition by Thomas Macdonald 1901346560 9781901346565 Full chapter

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Immunology for Gastroenterologists 1st Edition Thomas T. Macdonald Digital Instant Download

Author(s): Thomas T. Macdonald, Adrian C., M.D. Bateman
ISBN(s): 9781901346565, 1901346560
Edition: 1
File Details: PDF, 4.68 MB
Year: 2006
Language: english
SKU: EB-1392458 Category: Tags: , ,

Immunology and Diseases of the Gut 1st Edition by Thomas T. Macdonald – Ebook PDF Instant Download/Delivery: 1901346560, 978-1901346565
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ISBN 10:         1901346560
ISBN 13: 978-1901346565
Author:          Thomas T. Macdonald

Immunology and Diseases of the Gut (1st Edition) provides a comprehensive examination of the immune system’s role in gastrointestinal health and disease. This book explores the intricate relationship between gut immunity, the gut microbiome, and various gastrointestinal disorders, offering a detailed understanding of how immune responses are critical to maintaining gut homeostasis and how their dysfunction leads to diseases.

The book covers key topics such as the structure and function of the gut-associated lymphoid tissue (GALT), the role of mucosal immunity in protecting the gut, and how interactions between the immune system and the microbiome influence overall gut health. It also delves into immune-mediated diseases, including Inflammatory Bowel Disease (IBD), celiac disease, and gastrointestinal cancers, discussing their pathophysiology, immune mechanisms, and current treatment options.

Additionally, the text addresses the role of gut immunity in infectious diseases, the relationship between gut health and systemic conditions like metabolic syndrome, and the emerging research in gut immunology, including the potential of probiotics and prebiotics in therapeutic interventions.

Written for students, clinicians, and researchers, this book offers a blend of fundamental immunology and clinical insights, equipping readers with an understanding of both basic and advanced concepts in gut immunology. It provides valuable knowledge for advancing both the science of immunology and the clinical management of gut-related diseases.

Immunology and Diseases of the Gut 1st Table of contents:

    1. Introduction

      • Overview of Gut Immunology
      • The Importance of the Gut in Immune Responses
      • Key Concepts and Terminology

    2. Chapter 1: The Immune System of the Gut

      • Structure and Function of the Gut-associated Lymphoid Tissue (GALT)
      • The Role of Mucosal Immunity in Gut Health
      • Interaction Between Gut Microbiota and the Immune System

    3. Chapter 2: The Gut Microbiome and Immune Modulation

      • Composition of the Gut Microbiome
      • Mechanisms of Microbiota-Immune System Interaction
      • Dysbiosis and Its Impact on Health

    4. Chapter 3: Mucosal Immunity and the Gut Barrier

      • The Role of Epithelial Cells in Immune Defense
      • Secretory IgA and Other Immune Mediators in the Gut
      • Mechanisms of Immune Tolerance and Regulation

    5. Chapter 4: Innate and Adaptive Immunity in the Gut

      • Cells Involved in Gut Innate Immunity (Macrophages, Dendritic Cells, etc.)
      • Adaptive Immunity in the Gut: T Cells, B Cells, and Antibodies
      • The Role of Cytokines in Gut Immunity

    6. Chapter 5: Inflammatory Bowel Disease (IBD)

      • Overview of Crohn’s Disease and Ulcerative Colitis
      • Pathophysiology and Immune Mechanisms in IBD
      • Current Treatments and Future Therapies

    7. Chapter 6: Celiac Disease and Immune Responses to Gluten

      • Pathogenesis of Celiac Disease
      • Role of the Immune System in Gluten Sensitivity
      • Diagnosis and Management of Celiac Disease

    8. Chapter 7: Gut-Associated Lymphoid Tissue and Cancer

      • The Role of GALT in Gastrointestinal Cancer
      • Immune Surveillance and Tumor Immunology
      • The Impact of Inflammation on Cancer Development

    9. Chapter 8: Infectious Diseases of the Gut

      • Immune Responses to Gastrointestinal Infections
      • Role of Gut Immunity in Viral, Bacterial, and Parasitic Infections
      • Examples of Gut-Related Infections and Their Impact on Immune Function

    10. Chapter 9: Gut Immunity and Systemic Diseases

    • Gut as a Source of Systemic Inflammation
    • The Link Between Gut Health and Diseases Like Metabolic Syndrome and Cardiovascular Disease
    • The Gut-Brain Axis: Impact on Neurological Health
    1. Chapter 10: Emerging Research and Future Directions
    • Advances in Gut Immunology
    • The Role of Probiotics and Prebiotics in Immune Modulation
    • The Potential for Personalized Gut Health Therapies

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