High Throughput Analysis for Early Drug Discovery 1st Edition by James Kyranos ISBN 0124311657 978-0124311657
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Product details:
ISBN 10: 0124311657
ISBN 13: 978-0124311657
Author: James Kyranos
High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic chemists who need to set up appropriate characterisation methods for his/her organisation. This is an invaluable resource for all organic and analytical chemists in the pharmaceutical, agrochemical, and biotechnology fields who are either involved in, or beginning to investigate combinatorial techniques to increase overall efficiency and productivity.
First reference to focus on the analytical side of synthesis
Table of contents:
1 Analysis of a Combinatorial Library Synthesized Using a Split and Pool Irori MicroKan Method for Development and Production
2 High Throughput Flow Injection Analysis Mass Spectrometry
3 High Throughput Flow Injection Analysis Mass Spectrometry for Combinatorial Chemistry Using Electrospray Ionization Atmospheric Pressure
4 Purity and Quantity Determination of Parallel Synthesis Compound Libraries
5 High Throughput Parallel LCMS ELSD of Combinatorial Libraries Using the Eight-Channel LCT System with MUX Technology
6 Purification and Analysis of Parallel Libraries
7 Screening Single-Bead Combinatorial Libraries Using Capillary HPLC and MALDI-TOF MS
8 The Role of NMR in the Analysis of Chemical Libraries
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Tags:
James Kyranos,High Throughput,Early Drug