Genomics Fundamentals and Applications 1st Edition by Choudhuri Supratim, David Carlson ISBN 978-8126547494 8123914822

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ISBN 10:   8123914822

ISBN 13:  978-8126547494

Author: Choudhuri Supratim, David B. Carlson

This unique new text delivers a solid foundation for understanding the role of genomics in human health and in advances that promise to help improve the quality of human life. Unlike other works that focus mainly on toxicogenomic techniques, Genomics presents a thorough overview of the field in four major sections: 1) fundamentals of genes and genome structure, function, expression, variations, and genomic technology platforms; 2) applications of genomics in drug discovery and drug development, safety evaluation, genomic database maintenance, mining, and analysis, food safety monitoring, and translational toxicogenomics; 3) how regulatory agencies such as the FDA and EPA use genomic data in their safety evaluation; and 4) a summary of the current state and the future prospect of the science of genomics.

With an international perspective and practical case studies, Genomics is the first resource to present essential discussion of theory and application for:

• eukaryotic genomes
• epigenomics
• translational genomics and biomarker development

Table of contents: 

1. Fundamentals of Eukaryotic Gene Structure and Function
2. Genomes – A Brief Eukaryotic Perspective
3. Epigenomes – Beyond Genes and Genomes
4. Principles of Functional Genomic Analysis
5. Collaborations Lay the Critical Path
6. Functional Genomic Approaches
7. Immunotoxicogenomics
8. Human Genomics in Hypertension
9. Translational Toxicogenomics
10. Mining of Genome Sequence Databases
11. Microbial Genomics
12. Features and Functionality of Public Databases
13. Toxicogenomics in Non-Clinical Safety Studies
14. Strategies for Quality Assurance
15. Genomics and Drug Discovery
16. Physiological Genomic Approaches
17. Nutrigenomic Approaches
18. Use of Pharmacogenomic Data
19. US EPA
20. Review and Summary

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Tags: Choudhuri Supratim, David Carlson, Genomics Fundamentals