Genetics of Steroid Biosynthesis And Function 1st Edition by Mason ISBN 978-0415278782 0415278782

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Product details: 

ISBN 10: 0415278782

ISBN 13: 978-0415278782

Author:  J.I. Mason 

Steroids are among the most widely prescribed drugs for humans, and steroid signaling pathways are present in vertebrates, plants, insects and fungi, presenting new avenues for biotechnological intervention. Genetics of Steroid Biosynthesis and Function focuses on the genetic and cellular aspects of mammalian steroid hormones with particular attention to inherited gene lesions. With contributions from a panel of international experts, this volume provides an accessible, up-to-date overview of modern steroid biology for both the professional and novice researcher alike.

Table of contents: 

1. Steroid Biosynthesis: Enzymology, Integration and Control

2. Sterol Biosynthesis

3. Vitamin D Biosynthesis and its Disorders

4. Bile Acid Biosynthesis

5. Cholesterol Metabolism in Steroidogenic Tissues

6. Steroid 21-Hydroxylase

7. Steroid 11ß-Hydroxylase Isozymes

8. 3ß-Hydroxysteroid Dehydrogenase/Isomerase Deficiency

9. Human 17α-Hydroxylase/17,20-Lyase

10. Aromatase: Insights into the Roles of Estrogens Revealed by Natural and Targeted Mutations

11. 17ß-Hydroxysteroid Dehydrogenase and 5α-Reductase Deficiencies

12. Steroid Metabolism in Peripheral Tissues

13. Animal Models of Impaired Steroidogenesis

14. Regulation of Gene Expression by the Nuclear Receptor Family

15. Neurosteroids and Brain Sterols

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Tags: Mason, Genetics of Steroid, Biosynthesis And Function