Evidence Based Diagnosis Practical Guides to Biostatistics and Epidemiology 1st Edition by Thomas Newman, Michael Kohn ISBN 978-0521886529 052188652X
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Product details:
ISBN 10: 052188652X
ISBN 13: 978-0521886529
Author: Thomas B. Newman, Michael A. Kohn
Evidence-Based Diagnosis is a textbook about diagnostic, screening, and prognostic tests in clinical medicine. The authors’ approach is based on many years of experience teaching physicians in a clinical research training program. Although requiring only a minimum of mathematics knowledge, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. The book will be helpful and accessible to anyone seeking to select, develop, or market medical tests. Topics covered include: the diagnostic process, test reliability and accuracy, likelihood ratios, and ROC curves, testing and treatment thresholds, critical appraisal of studies of diagnostic, screening and prognostic tests, test independence and methods of combining tests, quantifying treatment benefits using randomized trials and observational studies, Bayesian interpretation of P values and confidence intervals and challenges for evidence-based diagnosis and evidence-based medicine.
Table of contents:
1 Introduction: understanding diagnosis and diagnostic testing
2 Reliability and measurement error
3 Dichotomous tests
4 Multilevel and continuous tests
5 Critical appraisal of studies of diagnostic tests
6 Screening tests
7 Prognostic tests and studies
8 Multiple tests and multivariable decision rules
9 Quantifying treatment effects using randomized trials
10 Alternatives to randomized trials for estimating treatment effects
11 Understanding P-values and confidence intervals
12 Challenges for evidence-based diagnosis
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Tags: Thomas Newman, Michael Kohn, Evidence Based, Diagnosis Practical