(Ebook PDF) Emerging Cancer Therapy Microbial Approaches and Biotechnological Tools Wiley Series in Biotechnology and Bioengineering 1st edition by Arsenio Fialho, Ananda Chakrabarty ISBN 9780470626511 0470626518 full chapters

(Ebook PDF) Emerging Cancer Therapy Microbial Approaches and Biotechnological Tools Wiley Series in Biotechnology and Bioengineering 1st Edition by  Ananda Chakrabarty, Arsenio Fialho  -Ebook PDF Instant Download/Delivery:9780470626511, 0470626518

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Product details:

ISBN 10:0470626518

ISBN 13:9780470626511

Author: : Dr. Arsenio Fialho, Ananda Chakrabarty

Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells.

This book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancertargeting molecules. In addition, the book highlights the benefits of a multi-target approach to destroy cancer cells. Readers will not only discover the results and significance of basic and clinical research, but also encouraging results from clinical trials.

Table of Contents:

Part I: Live/Attenuated Bacteria and Viruses as Anticancer Agents

1. Salmonella Typhimurium Mutants Selected to Grow Only in Tumors to Eradicate Them in Nude Mouse Models
2. The Use of Living Listeria Monocytogenes as an Active Immunotherapy for the Treatment of Cancer
3. Bacillus Calmette–Guerin (BCG) for Urothelial Carcinoma of the Bladder
4. Live Clostridia: A Powerful Tool in Tumor Biotherapy
5. Bifidobacterium as a Delivery System of Functional Genes for Cancer Gene Therapy
6. Replication-Selective Viruses for the Treatment of Cancer
7. Engineering Herpes Simplex Virus for Cancer Oncolytic Virotherapy

Part II: Bacterial Products as Anticancer Agents

8. Promiscuous Anticancer Drugs from Pathogenic Bacteria: Rational Versus Intelligent Drug Design
9. Arginine Deiminase and Cancer Therapy
10. Cytosine Deaminase/5-Fluorocytosine Molecular Cancer Chemotherapy
11. Bacterial Proteins against Metastasis
12. Pseudomonas Exotoxin A-Based Immunotoxins for Targeted Cancer Therapy
13. Denileukin Diftitox in Novel Cancer Therapy
14. The Application of Cationic Antimicrobial Peptides in Cancer Treatment: Laboratory Investigations and Clinical Potential
15. Prodiginines and Their Potential Utility as Proapoptotic Anticancer Agents
16. Farnesyltransferase Inhibitors of Microbial Origins in Cancer Therapy
17. The Use of RNA and CpG DNA as Nucleic Acid-Based Therapeutics

Part III: Patents On Bacteria/Bacterial Products as Anticancer Agents

18. The Role and Importance of Intellectual Property Generation and Protection in Drug Development

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Arsenio Fialho,Ananda Chakrabarty,Emerging Cancer Therapy,Microbial,Biotechnological Tools