Deformation Mechanisms Rheology and Tectonics From Minerals to the Lithosphere Geological Society Special Publication 1st Edition by Cobbold, Brun, Gapais ISBN 978-1862391765 1862391769

Deformation Mechanisms Rheology and Tectonics From Minerals to the Lithosphere Geological Society Special Publication 1st Edition by  P.R. Cobbold,  J.-P. Brun,  D. Gapais – Ebook PDF Instant Download/Delivery:  978-1862391765, 1862391769
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Product details: 

ISBN 10:   1862391769

ISBN 13: 978-1862391765

Author:  P.R. Cobbold,  J.-P. Brun,  D. Gapais

This book consists of 18 papers on deformation mechanisms, rheology and tectonics. The main approaches include experimental rock deformation, microstructural analysis, field structural studies, analogue and numerical modeling. New results on various topics are presented, ranging from brittle to ductile deformation and grain-scale to lithosphere-scale mechanisms. The volume contains review papers on several major current topics, such as the rheology of the lithospheric mantle and the mechanisms of exhumation of high-pressure tectonic units, as well as research papers on kinematic and mechanical analysis of rock deformation and related new techniques. Several contributions emphasize the increasing ability and wish of researchers to strengthen the links between small-scale physical mechanisms and large-scale tectonics. The volume will be of interest to academic and industrial researchers in the fields of structural geology, interactions between metamorphism, fluids and deformation, and large-scale tectonic processes.Also available

Table of contents: 

Session I: Screening models

1. The human γ-aminobutyric acid transporter GAT-2: from cloning to high throughput screening
   Bolette Christiansen, Trine Kvist, Anders A. Jensen, and Hans Bräuner-Osborne

2. Low throughput preclinical models for headache
   Peter J. Goadsby

3. Human models: screening models
   Messoud Ashina

Session II: Trials methodology

4. Stricter success criteria, qualitative and quantitative end-points: acute versus prevention trials
   Peer Tfelt-Hansen

5. Health-related quality of life and similar end-points
   Carl G.H. Dahlöf

6. Clinically relevant designs and outcome measures for acute migraine trials
   Michel D. Ferrari and Hille Koppen

7. Effectiveness of different steroid dosage in Tolosa-Hunt syndrome with different phenotypes: some critical points about the new International Headache Society classification
   E. Marchioni, S. Colnaghi, M. Versino, A. Pichiecchio, E. Tavazzi, and G. Nappi

8. Discussion summary: Trials methodology
   Jes Olesen

Session III: Nitric oxide and spreading depression modulators

9. Inducible nitric oxide synthase and development of new migraine treatments
   Boris A. Chizh

10. Mechanisms of cortical spreading depression as targets for migraine therapy
    Kevin C. Brennan and Andrew C. Charles

11. ToneBersat
    Peter R. Blower and Paul C. Sharpe

12. Discussion summary: Nitric oxide and spreading depression modulators
    Nabih Ramadan

Session IV: Calcitonin gene-related peptide and 5-hydroxytryptamine modulators

13. Calcitonin gene-related peptide: relevance for migraine
    Jes Olesen and Inger Jansen-Olesen

14. New 5-hydroxytryptamine-related drug targets
    Pramod R. Saxena

15. Effect of two novel calcitonin gene-related peptide-binding compounds in a closed cranial window rat model
    Louise Juhl, Lars Edvinsson, Jes Olesen, and Inger Jansen-Olesen

16. Vasoactive intestinal polypeptide is unlikely to be a target for headache and migraine treatment
    Jakob Møller Hansen, Alexandra Maria Rahmann, Jes Olesen, and Messoud Ashina

17. Discussion summary: Calcitonin gene-related peptide and 5-hydroxytryptamine modulators
    Rigmor Jensen

Session V: Ion channel modulators and antiepileptics

18. Migraine: from genes to pathophysiology – transgenic mouse models of migraine
    Arn M.J.M.

19. KATP channels and migraine
    Inger Jansen-Olesen and Kenneth Beri Ploug

20. Antiepileptic drugs and migraine
    Michael A. Rogawski

21. Discussion summary: Ion channel modulators and antiepileptics
    Pramod R. Saxena

Session VI: Other future targets for headache therapy

22. Innovative drug development for headache disorders: glutamate
    Kirk W. Johnson, Eric S. Nisenbaum, Michael P. Johnson, Donna K. Dieckman, Amy Clemens-Smith, Edward R. Siuda, Colin P. Dell, Veronique Dehlinger, Kevin J. Hudziak, Sandra A. Filla, Paul L. Ornstein, Nabih M. Ramadan, and David Bleakman

23. The modulation of TRPV1 channels by cannabinoid receptors
    Beatriz Fioravanti and Todd W. Vanderah

24. Future targets for headache therapy: prostanoids
    Christian Waeber

25. Role of anandamide in the modulation of nitroglycerin-induced hyperalgesia: a study in the rat
    Cristina Tassorelli, Rosaria Greco, Armando Perrotta, Simona Buscone, Giorgio Sandrini, and Giuseppe Nappi

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Tags: Cobbold, Brun, Gapais, Deformation Mechanisms, Rheology and Tectonics, the Lithosphere