Cortical Development Genes and Genetic Abnormalities 1st Edition by Jamie Goode, Gregory Bock ISBN 978-0470060926 0470060921

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Product details: 

ISBN 10:  0470060921

ISBN 13: 978-0470060926

Author: Jamie A. Goode, Gregory R. Bock

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime.  This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system.
Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical arealisation, and disorders which can arise from incorrect arealisation; genes implicated in the development of cortical connectivity and related pathologies such as schizophrenia and synaesthesia; and susceptibility genes for cognitive disorders such as schizophrenia, autism, dyslexia, and attention deficit disorder.

Table of contents: 

1. Symposium on Cortical development: genes and genetic abnormalities, held at the Novartis Foundation, London, 6-8 February 2007
   Editors: Gregory Bock (Organizer) and Jamie Goode
   This symposium is based on a proposal made by Zoltán Molnár

2. John G. Parnavelas Chair’s introduction

3. Bradley J. Molyneaux, Paola Arlotta and Jeffrey D. Macklis
   Molecular development of corticospinal motor neuron circuitry

4. Discussion

5. Gordon Fishell
   Perspectives on the developmental origins of cortical interneuron diversity

6. Discussion

7. Pasko Rakic, Kazue Hashimoto-Torii and Matthew R. Sarkisian
   Genetic determinants of neuronal migration in the cerebral cortex

8. Discussion

9. Stephen C. Noctor, Veronica Martinez-Cerdeño and Arnold R. Kriegstein
   Neural stem and progenitor cells in cortical development

10. Discussion

11. Teresa H. Chae and Christopher A. Walsh
    Genes that control the size of the cerebral cortex

12. Discussion

13. General discussion I

14. Vicki Hammond, Joanne Britto, Eva So, Holly Cate and Seong-Seng Tan
    Control of cortical neuron layering: lessons from mouse chimeras

15. Discussion

16. Fujio Murakami, Daisuke Tanaka, Mitsutoshi Yanagida and Emi Yamazaki
    Intracortical multidirectional migration of cortical interneurons

17. Discussion

18. Libing Zhou, Fadel Tissir and André M. Goffinet
    The atypical cadherin Celsr3 regulates the development of the axonal blueprint

19. Discussion

20. Dennis D. M. O’Leary, Shen-Ju Chou, Tadashi Hamasaki, Setsuko Sahara, Akihide Takeuchi, Sandrine Thuret and Axel Leingärtner
    Regulation of laminar and area patterning of mammalian neocortex and behavioural implications

21. Discussion

22. Jeremy A. Cholfin and John L. R. Rubenstein
    Genetic regulation of prefrontal cortex development and function

23. Discussion

24. Henry Kennedy, Rodney Douglas, Kenneth Knoblauch and Colette Dehay
    Self-organization and pattern formation in primate cortical networks

25. Discussion

26. Nobuhiko Yamamoto, Takuro Maruyama, Naofumi Uesaka, Yasufumi Hayano, Makoto Takemoto, and Akito Yamada
    Molecular mechanisms of thalamocortical axon targeting

27. Discussion

28. Zoltan Molnar, Anna Hoerder-Suabedissen, Wei Zhi Wang, Jamin DeProto, Kay Davies, Sheena Lee, Erin C. Jacobs, Anthony T. Campagnoni, Ole Paulsen, Maria Carmen Piñon, and Amanda FP Cheung
    The earliest cortical circuits

29. Discussion

30. Michael Piper, Amber-Lee S. Dawson, Charlotta Lindwall, Guy Barry, Céline Plachez and Linda J. Richards
    Emx and Nfi genes regulate cortical development and axon guidance in the telencephalon

31. Discussion

32. Paul J. Harrison
    Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1

33. Discussion

34. Peter B. Crino
    Focal brain malformations: a spectrum of disorders along the mTOR cascade

35. Discussion

36. Final discussion

37. Index of contributors

38. Subject index

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Tags: Jamie Goode, Gregory Bock, Cortical Development, Genetic Abnormalities