Chirality in Drug Design and Development 1st Edition by Indra K. Reddy, Reza Mehvar- Ebook PDF Instant Download/Delivery: 978-0824750626, 0824750626
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Product details:
ISBN 10: 0824750626
ISBN 13: 978-0824750626
Author: Indra K. Reddy, Reza Mehvar
Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.
Table of contents:
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Impact of crystal structure and physical properties on chiral drug release
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Role of chiral excipients in drug formulations
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Mechanisms of chiral molecule transport across the skin
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Prodrug approaches for stereoselective drug delivery
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Overview of stereoselectivity in drug action and disposition
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Stereospecific pharmacokinetics and pharmacodynamics in various drug classes
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Focus on cardiovascular drugs and stereospecific effects
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Chiral inversion processes
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Importance of stereospecific assays in bioequivalency of racemic drugs
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Regulatory aspects in developing stereoisomeric drugs
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Tags: Indra Reddy, Reza Mehvar, Chirality in Drug, Design and Development


