Sale!

Capillary Electrophoresis of Carbohydrates 1st Edition by Pierre Thibault, Susumu Honda ISBN 978-1617372063 1617372064

Original price was: $50.00.Current price is: $35.00.

Capillary Electrophoresis of Carbohydrates 1st Edition. Edition Pierre Thibault Digital Instant Download

Author(s): Pierre Thibault, Susumu Honda
ISBN(s): 9781617372063, 1617372064
Edition: 1st Edition.
File Details: PDF, 1.78 MB
Year: 2010
Language: english
SKU: EB-931564 Category: Tags: ,

Capillary Electrophoresis of Carbohydrates 1st  Edition by Pierre Thibault, Susumu Honda – Ebook PDF Instant Download/Delivery:  978-1617372063, 1617372064
Full download Capillary Electrophoresis of Carbohydrates 1st  Edition after payment

Product details: 

ISBN 10:   1617372064

ISBN 13: 978-1617372063

Author:  Pierre Thibault, Susumu Honda

Glycoconjugates such as glycoproteins and glycolipids play important roles in cell-cell interaction events, including development, differentiation, m- phogenesis, fertilization, inflammation, and metastasis. A number of reports have documented the association of unique oligosaccharide sequences to p- tein targeting and folding, and in mechanisms of infection, inflammation, and immunity. For glycoproteins, these glycan appendages are the result of extensive co- or post-translational modifications of the nascent proteins in the endoplasmic reticulum and in the Golgi apparatus. Although nucleic acids and proteins are copied from a template in a repeated series of identical steps using the same enzymes, complex carbohydrates are formed by the sequential actions of cellular glycosyltransferases that specifically recognize unique s- strates. The molecular biology of these transferases and other carbohydra- modifying enzymes is providing important insights on oligosaccharide recognition events. While it is acknowledged that the definition of the protein complement of cells and tissues (the so-called proteome) remains an enormous task in this postgenomic era, the characterization of all glycans produced by individual organisms (referred to as the glycome) presents an equally imp- tant challenge. This task is further complicated by the fact that oligosacc- rides cannot presently be cloned. These complex carbohydrates exist in a staggering diversity of structures, linkages, and branching, thus providing an exquisite molecular repertoire for cellular interactions.
 

Table of contents: 

  1. Structural and Functional Diversity of Glycoconjugates

  2. Sample Preparation Methods

  3. Chemical and Enzymatic Release of Glycans from Glycoproteins

  4. Derivatization of Carbohydrates

  5. Preparation of Oligosaccharides from Sulfated Glycosaminoglycans Using Bacterial Enzymes

  6. Analysis of Mono- and Oligosaccharides

  7. Monosaccharide Analysis by Capillary Electrophoresis

  8. Separation of Oligosaccharides by Capillary Electrophoresis Using Buffer Modifiers

  9. Characterization of Oligosaccharides from Starch, Dextran, Cellulose, and Glycoproteins by Capillary Electrophoresis

  10. Affinity Capillary Electrophoresis of Oligosaccharides

  11. Characterization of Glycosaminoglycans by Capillary Electrophoresis

  12. Analysis of Glycoconjugates and the Component Monosaccharides

  13. Analysis of 2-Aminoacridone-Derivatized Complex Oligosaccharides Using Micellar Electrokinetic Capillary Chromatography and Laser-Induced Fluorescence Detection

  14. Separation of Protein Glycoforms by Capillary Electrophoresis

  15. Separation of Glycoproteins by Capillary Isoelectric Focusing

  16. Glycoprotein Analysis by Capillary Zone Electrophoresis–Electrospray Mass Spectrometry

  17. Analysis of Bacterial Glycolipids by Capillary Electrophoresis–Electrospray Mass Spectrometry

  18. Specific Applications

  19. Capillary Electrophoresis as an Assay Method for Monitoring Glycosyltransferase Activity

  20. Determination of Association Constant of Carbohydrate-Protein Interaction

People also search for:

    
capillary electrophoresis of carbohydrates
    
what is capillary electrophoresis
    
history of capillary electrophoresis
    
how does capillary electrophoresis work
    
capillary electrophoresis of proteins

Tags: Pierre Thibault, Susumu Honda, Capillary Electrophoresis