(Ebook PDF) Antigenic Variation 1st Edition by Alister Craig,Artur Scherf -Ebook PDF Instant Download/Delivery: 9781423755388, 1423755383
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Product details:
ISBN 10:1423755383
ISBN 13: 9781423755388
Author: Alister G. Craig, Artur Scherf
The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms ‘shift shape’, by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body.The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites – one of the most fascinating groups of organisms exhibiting this behaviour.
Table of Contents:
- Synthesis of allelic/antigenic variation
- HIV variation – a question of signal-to-noise
- Calicivirus
- Influenza, the chameleon virus
- Rotaviruses
- Mycoplasma
- Haemophilus Influenzae
- Phase Variation in Helicobacter pylori Lipopolysaccharide
- Genetic Variation in the Pathogenic Neisseria Species
- Candida Albicans
- The MSG Gene Family and Antigenic Variation in the Fungus P. carinii
- Trypanosome Antigenic Variation – a heavy investment in the evasion of immunity
- Antigenic variation in Anaplasma marginale and Ehrlichia (Cowdria) ruminantium
- Antigenic Variation and its’ Significance to Babsesia
- Antigenic Variation in Plasmodium falciparum and other Plasmodium
- Species
- Antigenic Variation in Borrelia: Relapsing Fever and Lyme Borreliosis
- Surface Antigenic Variation in Giardia lamblia
- Free-living and Parasitic Ciliates:The Impact of Antigenic Variation on Pathogen Population
- Structure, Fitness and Dynamics
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Antigenic Variation,Alister Craig,Artur Scherf