Advances in Immunology 1st Edition by Frederick Alt, Kenneth Murphy ISBN 978-0443222368 0443222363
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Product details:
ISBN 10: 0443222363
ISBN 13: 978-0443222368
Author: Frederick W. Alt, Kenneth Murphy
Advances in Immunology, Volume 160, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Focuses on recent advances in t cells and HIV infection
Table of contents:
1. Introduction
2. TCR Signaling Leading to Actin Cytoskeletal Remodeling
2.1. Proximal signals from the TCR to actin nucleation
2.2. Generation of F-actin in T cells by ARP2/3 regulators
2.3. Formin-mediated F-actin nucleation in T cells
2.4. Up-and-coming regulators of F-actin in T cells
3. Cytoskeletal Control of IS Formation
3.1. The immunological synapse
3.2. What are TCR microclusters?
3.3. Potential links between the T cell cytoskeleton and TCR-MCS
3.4. New perspectives: VAVI, WASP, and IS formation
3.5. ERM family proteins and the distal pole complex
4. Regulation of TCR-Mediated MTOC Polarization
5. F-Actin-Mediated Regulation of Integrins
5.1. Integrin overview
5.2. RAPI regulation of integrins
5.3. WAVE2 as a key regulator of integrins
6. Cytoskeletal Dynamics and Cell Migration
6.1. Polarity during T cell migration
6.2. Chemokine signaling to F-actin remodeling and cell motility
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