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Serotonin Receptor Technologies 1st Edition by Wolfgang Blenau, Arnd Baumann ISBN 978-1493921867 149392186X

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Serotonin Receptor Technologies 1st Edition Wolfgang Blenau Digital Instant Download

Author(s): Wolfgang Blenau, Arnd Baumann (eds.)
ISBN(s): 9781493921867, 149392186X
Edition: 1
File Details: PDF, 6.89 MB
Year: 2015
Language: english
SKU: EB-4950044 Category: Tags: ,

Serotonin Receptor Technologies 1st Edition by Wolfgang Blenau, Arnd Baumann  – Ebook PDF Instant Download/Delivery: 978-1493921867, 149392186X
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Product details: 

ISBN 10:  149392186X

ISBN 13: 978-1493921867

Author: Wolfgang Blenau, Arnd Baumann

Reflecting a vast amount of new information concerning the functional characteristics of the various 5-HT receptor subtypes and the Na+-dependent serotonin transporter (SERT), this volume provides state of the art methodologies currently applied in serotonin research from leading experts in the field. Serotonin Receptor Technologies describes approaches that vary from molecular biological and biochemical techniques (e.g., regarding receptor dimerization), fluorescence microscopy and imaging applications, flow cytometry, the use of organotypic slice and cell cultures to the generation of genetically modified animal models and the development of sophisticated behavioral tests, thus covering a wide spectrum of techniques to study serotonergic signaling in detail. Written for the popular Neuromethods series, chapters include the kind of detail and practical advice that ensures successful results in the lab.

Authoritative and convenient, Serotonin Receptor Technologies serves to foster both basic and translational research aiming to further deepen our understanding of the various facets of aminergic systems, as well as to aid research on similar problems with related GPCRs and neurotransmitter transporters.

Table of contents: 

PART I

RECEPTOR DIMERIZATION

1 Novel Approaches to Serotonin Receptor Interaction Studies Sylwia Łukasiewicz, Ewa Błasiak, Kinga Szafran-Pilch, and Marta Dziedzicka-Wasylewska

2 Techniques for the Study of GPCR Heteromerization in Living Cells and Animal Models.

Jose L. Moreno, Jeremy Seto, James B. Hanks and Javier Gonzalez-Maeso

PART II

MANIPULATION AND ANALYSIS OF SEROTONERGIC SIGNALING IN BRAIN SLICES

3 Organotypic Slices and Biolistic Transfection for the Study of Serotonin Receptor Function in CNS Neurons. Kelly McGregor, Jean-Claude Beïque, and Rodrigo Andrade

PART III

MOUSE MODELS TO STUDY SEROTONIN-ASSOCIATED BEHAVIORAL DISORDERS

4 Dissecting a Model of Depressive-Related Phenotype and Antidepressant Effects in 129S2/SvPas Mice Silvina L. Diaz and Luc Maroteaux

5 The Murine Serotonin Syndrome and the 5-HTIA Receptor: Behavioral Effects and Hypothermia Robert Haberzettl, Heidrun Fink, Silke Dietze, and Bettina Bert

6 5-HT, Receptor Subtype, ẞ-Arrestin Level, and Rapid-Onset Effects of Antidepressant Drugs Indira Mendez-David, Denis Joseph David, Jean-Philippe Guilloux, René Hen, and Alain Michel Gardier

PART IV

SEROTONIN TRANSPORTER

7 Autoshaping Memory Formation and Retention Loss: Are Serotonin and Other Neurotransmitter Transporters Involved?. Alfredo Meneses and Ruth Tellez

8 Flow Cytometry to Determine Serotonin Transporter Function in Human Peripheral Blood Cells Brendan S. Beikmann and Anne M. Andrews

PART V INVERTEBRATE MODEL SYSTEMS

9 Functional Genomics of Serotonin Receptors in Helminth Parasites:

Elucidation of Receptor Function Through RNA Interference (RNAi)

Mohammed Rashid, Kevin MacDonald, and Paula Ribeiro

10 Visualization of the Serotonin System in Drosophila Brain: Immunofluorescence and Confocal Microscopy.

Charles D. Nichols and Kelly Jean Sherman

11 Serotonin Modulates Adult Neurogenesis in an Invertebrate Model:

Approaches to Receptor Localization and Function. Barbara S. Beltz, Yi Zhang, and Jeanne L. Benton

12 Immunolocalization of Serotonergic Neurons in Arthropod Developmental and Phylogenetic Neuroanatomy.

Torben Stemme and Michael Stern

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Tags: Wolfgang Blenau, Arnd Baumann, Serotonin Receptor Technologies