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(Ebook PDF) Atherosclerosis Molecular and Cellular Mechanisms 1st Edition by Sarah Jane George, Jason Johnson 3527324488 9783527324484 Full chapter

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Atherosclerosis Molecular and Cellular Mechanisms 1st Edition Sarah Jane George Digital Instant Download

Author(s): Sarah Jane George, Jason Johnson
ISBN(s): 9783527324484, 3527324488
Edition: 1
File Details: PDF, 5.04 MB
Year: 2010
Language: english
SKU: EB-1716504 Category: Tags: ,

Atherosclerosis Molecular and Cellular Mechanisms 1st Edition by Sarah Jane George, Jason Johnson – Ebook PDF Instant Download/Delivery: 3527324488, 978-3527324484
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Product details:

ISBN 10:         3527324488
ISBN 13: 978-3527324484
Author:          Sarah Jane George, Jason Johnson

With atherosclerosis being the number one cause of death in the western world, this handbook and ready reference provides a comprehensive account of the different stages and factors in the development of the atherosclerotic plaque.
Each chapter is written by experts in the field and highlights the role of specific mediators of atherosclerotic plaque development, as well as potential therapeutic targets. A large amount of this up-to-date information is conveyed by way of tables and schematic figures, in a readily comprehensible manner.
A must-have for master and PhD students, researchers, MDs and lecturers in vascular biology and cardiology, as well as for academics and scientists in the pharmaceutical industry.

Atherosclerosis Molecular and Cellular Mechanisms 1st Table of contents:

1. Introduction to Atherosclerosis

  • Definition and Overview
  • Historical Perspectives
  • Epidemiology of Atherosclerosis

2. Pathogenesis of Atherosclerosis

  • The Role of Endothelial Dysfunction
  • The Formation of Fatty Streaks
  • Progression to Atheromatous Plaques
  • Inflammation and Immune System Involvement

3. Molecular Mechanisms in Atherosclerosis

  • Lipid Metabolism and Atherosclerosis
  • Role of Low-Density Lipoprotein (LDL) and High-Density Lipoprotein (HDL)
  • Oxidative Stress and Its Contribution
  • Role of Inflammatory Cytokines

4. Cellular Mechanisms in Atherosclerosis

  • Endothelial Cells and Vascular Inflammation
  • Smooth Muscle Cell Migration and Proliferation
  • Macrophages and Foam Cells in Plaque Development
  • The Role of T-Cells and Other Immune Cells

5. Risk Factors for Atherosclerosis

  • Genetic Factors
  • Environmental Factors (Diet, Smoking, Physical Activity)
  • Metabolic Syndrome and Diabetes
  • Hypertension and Atherosclerosis

6. Genetic and Epigenetic Regulation in Atherosclerosis

  • Genetic Susceptibility and Atherosclerosis Development
  • Epigenetic Modifications and Their Impact
  • Role of MicroRNAs and Other Non-coding RNAs

7. Atherosclerosis and Cardiovascular Disease

  • Pathophysiology of Coronary Artery Disease
  • Atherosclerosis and Stroke
  • Peripheral Arterial Disease

8. Diagnostic Approaches to Atherosclerosis

  • Imaging Techniques (MRI, CT, Ultrasound)
  • Biomarkers of Atherosclerosis
  • Genetic Screening for Atherosclerosis

9. Therapeutic Strategies in Atherosclerosis

  • Statins and Lipid-Lowering Drugs
  • Anti-inflammatory Treatments
  • Novel Therapeutic Targets in Atherosclerosis
  • Lifestyle Modifications and Preventative Approaches

10. Future Directions in Atherosclerosis Research

  • Advances in Molecular and Cellular Mechanisms
  • Emerging Drug Therapies
  • Role of Precision Medicine in Atherosclerosis

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