Transfusion Free Medicine and Surgery 2nd Edition by Nicolas Jabbour ISBN 0470674083 9781118554715

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ISBN 10: 0470674083 
ISBN 13: 9781118554715
Author: Nicolas Jabbour

This book aims to be a guide to the practice of blood conservation. The first chapter discusses the legal and administrative aspects of bloodless medicine describing the legal principles and practical issues relatd to refusal of transfusion. The second is on balancing the risks and benefits of transfusion includes clinical vignettes of appropriate and inappropriate transfusion. The remainder of the book covers the principles and practice of bloodless medicine, including a chapter on the scientific issues of haemostasis and the investigation of bleeding idsorders. The book concludes with chapters on blood conservation in neonatal and paediatric surgery, the costs associated with blood transfusion and the quest for artifical blood. New chapters will be included to address blood utilization in oncology and geriatric patients.

Transfusion Free Medicine and Surgery 2nd Table of contents:

Chapter 1: History of blood transfusion and patient blood management
Introduction
Blood: early beliefs and practice
Blood transfusion
Transfusion with animal blood
First human blood transfusion
Karl Landsteiner to the twenty-first century
New transfusion issues emerge
The new paradigm
References
Chapter 2: The ethical complexities of transfusion-free medicine, surgery and research
Introduction
Ethics and informed consent
Children, assent, and consent
Professionalism and transfusion-free practices
Jehovah’s witnesses
Organ transplantation
Research ethics
References
Chapter 3: Transfusion therapy—Balancing the risks and benefits
Introduction/overview
The clinical utility of transfusion therapy
Summary and conclusions
References
Chapter 4: The physiology of anemia and the threshold for blood transfusion
Introduction
Etiologies of anemia
Physiologic response to anemia
The transfusion threshold
Risks of blood transfusion
Summary
References
Chapter 5: Blood transfusion in surgery
Introduction
The cost-effectiveness of blood products: a surgical perspective
Pre-operative optimization of the surgical patient
Intra-operative approach to blood conservation
Post-operative care
Trends in transfusion-free surgery
Conclusion
References
Chapter 6: Current view of coagulation system
Normal hemostasis
Regulation of hemostasis
Abnormal hemostasis
Evaluation of hemostasis
Management of intraoperative coagulation
Hemostatic drug therapy
References
Chapter 7: Topical hemostatic agents
Introduction
History of hemostatics
The biology of hemostasis
Hemostasis in surgery
Safety of hemostatics
Topical hemostatics
Adhesive hemostatics (fibrin glues)
Topical hemostatics (Passive agents)
References
Chapter 8: Intraoperative strategies for transfusion-free medicine
Introduction
General considerations
Autologous blood
Pharmacologic agents for blood conservation
Controlled hypotension
Summary
References
Chapter 9: Post-operative management in transfusion-free medicine and surgery in the ICU
Introduction
Anemia in the ICU
Role of transfusion in resuscitation
Monitoring the adequacy of oxygenation
Reducing transfusion requirements
Conclusion
References
Chapter 10: The changing transfusion practice of neonatal and pediatric surgery
Introduction
Transfusion considerations specific to the pediatric population
Strategies to limit need or transfusion
Applications of transfusion-limiting strategies to specific surgical situations
Conclusion
Acknowledgements
References
Chapter 11: Current management of anemia in oncology
Overview
Epidemiology and pattern of treatment
Prognostic significance and rationale for correcting anemia in oncology
Pathophysiology of anemia in cancer patients
Diagnostic evaluation and risk assessment
Treatment options
Peripheral red blood cell (PRBC) transfusion
Trend of increased transfusions because of decreased ESA use
Current recommendations
Evolving concepts
Conclusion
References
Chapter 12: Artificial blood
Background
Basics of blood oxygen transportation
Defining the need for artificial oxygen carriers
Hb-based oxygen carriers
Perfluorocarbons
Conclusion
References
Chapter 13: Translational strategies to minimize transfusion requirement in liver surgery and transplantation: Targeting ischemia-reperfusion injury
Introduction
Role of ischemia-reperfusion injury in liver surgery and transplantation
Surgical and pharmacological strategies to mimimize I/R injury in liver surgery and transplantation
Conclusion
References
Chapter 14: Legal and administrative issues related to transfusion-free medicine and surgery programs
Introduction
History of Jehovah’s Witnesses and blood
Acceptable products, treatments, and procedures
Overview of legal principles related to refusal of blood
Evolution of bloodless programs
Legal structure of bloodless program
Future expansion of transfusion-free programs
References
Chapter 15: Basic principles of bloodless medicine and surgery
Index
End User License Agreement

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Tags: Nicolas Jabbour, Transfusion, Medicine