Cellular Aspects of HIV Infection 1st Edition by David Kaplan – Ebook PDF Instant Download/Delivery: 0471459151, 9780471459156
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Product details:
ISBN 10: 0471459151
ISBN 13: 9780471459156
Author: David Kaplan
Cellular Aspects of HIV Infection provides a highly readable, detailed overview of the state of the art in modern HIV research at the cellular level. This volume brings together renowned experts who have provided concise, synthetic treatments of the biology of HIV infection. It presents these descriptions and analyses with particular attention to the techniques of flow cytometry that have allowed us to not only observe the course of HIV infection and the immune system’s response to it, but have also increased our ability to treat patients and understand their response to therapy.
The book is divided into five sections covering molecules and cells, pathophysiological processes, technologies, and organisms. A perspective on future therapies concludes the book. Each chapter offers an intelligent, concise synthesis of the topic, highlighting the biological principles and technologies involved in the study of HIV infection. Cellular Aspects of HIV Infection is an indispensable, up-to-date guide for immunologists, virologists, clinicians, and researchers.
Table of contents:
Part I: MOLECULES
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HIV and Molecular Biology of the Virus-Host Interplay — Massimo Clementi
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Telomere Length, CD28- T Cells, and HIV Disease Pathogenesis — Rita B. Effros
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Immune Dysregulation and T-Cell Activation Antigens in HIV Infection — Mara Biasin, Fulvia Colombo, Stefania Piconi, Mario Clerici
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Quantification of HIV/SIV Coreceptor Expression — Benhur Lee, Robert W. Doms
Part II: CELLS
5. B Cells in the Line of Sight of HIV-1 — Yolande Richard, Eric A. Lefevre, Roman Krzysiek, Christophe Legendre, Dominique Dormont, Pierre Galanaud, Gabriel Gras
6. Cytotoxic T-Cell (CTL) Function in HIV Infection — M. L. Garba, J. A. Frelinger
7. Analysis of the α/β T-Cell Receptor Repertoire in HIV Infection — Hugo Soudenys
8. Gamma-Delta (γδ) T Cells and HIV-1 Infection — Roxana E. Rojas, W. Henry Boom
9. Natural Killer Cells in HIV Infection and Role in the Pathogenesis of AIDS — Benjamin Bonavida
10. Alveolar Macrophages — Jianmin Zhang, Henry Koziel
11. Dendritic Cells Ferry HIV-1 from Periphery into Lymphoid Tissues — Teunis B. H. Geijtenbeek, Yvette van Kooyk
Part III: PROCESSES
12. Homeostasis and Restoration of the Immune System in HAART-Treated HIV-Infected Patients: Implications of Apoptosis — Marie-Lise Gougeon, Herve LeCoeur, Luzia Maria de Oliveira Pinto, Eric Ledru
13. Mitochondria Functionality During HIV Infection — Andrea Cossarizza, Marcello Pinti, Milena Nasi, Maria Garcia Fernandez, Laura Moretti, Cristina Mussini, Leonarda Troiano
14. Multiple Roles of Cytokines in HIV Infection, Replication, and Therapy — Massimo Alfano, Guido Poli
Part IV: TECHNOLOGIES
15. The Use of Peptide/MHC Tetramers to Visualize, Track, and Characterize Class I-Restricted Anti-HIV T-Cell Response — Clive M. Gray, Thomas C. Merigan
16. Tagging of HIV with Green Fluorescent Protein — Nadya I. Tarasova
17. Flow Cytometric Analysis of Cells from Persons with HIV-1 Disease by Enzymatic Amplification Staining — David Kaplan
18. Antigen-Specific Cytokine Responses in HIV Disease — Vernon C. Maino, Holden T. Maecker, Louis J. Picker
Part V: ORGANISMS
19. Chimeric Models of SCID Mice Transplanted with Human Cells: The Hu-PBL-SCID Mouse and Its Use in AIDS Research — S. M. Santini, C. Lapenta, M. Logozzi, S. Parlato, M. Spada, T. Di Pucchio, S. Fais, F. Belardelli
20. Immune Reconstitution of the CD4 T-Cell Compartment in HIV Infection — Guislaine Carcelain, Taisheng Li, Marc Renaud, Patrice Debre, Brigitte Autran
21. New Perspectives in Antiretroviral Therapy of HIV Infection — Stefano Vella
Index
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