State of the World s Vaccines and Immunization 3rd Edition by World Health Organization ISBN 978-9241563864 9241563869

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Product details: 

ISBN 10: 9241563869

ISBN 13:  978-9241563864

Author: World Health Organization

This report is a call to action to governments and donors to sustain and increase funding for immunization in order to build upon the progress made so far in meeting the global goals. The price of failure will be counted in children’s lives.

This new edition of the State of the World’s Vaccines and Immunization focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the MDGs, especially the goal to reduce deaths among children under five. It looks at the development and use of vaccines and at the safeguards that have been put in place to ensure their safety, efficacy, and quality. It sets out the progress and challenges in meeting the immunization-related global goals, and looks at the cost of scaling up immunization coverage to meet these goals, and efforts to ensure that the achievements are sustainable in the long term. Finally, it looks beyond 2015 to likely changes in the immunization landscape.

Part 2 focuses on over 20 vaccine-preventable diseases and reviews progress since 2000 in efforts to protect populations against these diseases through the use of vaccines.

Table of contents: 

PART 1: Progress and challenges in meeting global goals

1. Immunization and human development

2. A new chapter in vaccine development

A vaccine boom

Explaining the new momentum

Technology comes of age

Reverse technology

Conjugation technology

Adjuvants

Cell substrates

New licensed vaccines

Vaccines in the pipeline

Supplying vaccines for a changing world

A rapidly expanding market

A concentrated industry

Planning, producing, protecting

Towards vaccines of assured quality

Making and meeting standards of quality and safety

Strengthening national regulatory authorities

A regulators’ network for developing countries

Harmonizing and standardizing vaccine regulation

Innovative regulatory pathways

3. Immunization: putting vaccines to good use

The unfinished immunization agenda

Extending the benefits of immunization equitably within countries

Reaching more children through campaign strategies

Greater awareness fuels demand

Surveillance and monitoring: essential health system functions

Optimizing the delivery of vaccines

Linking interventions for greater impact

Combating fear with knowledge and evidence

Remarkable progress, huge challenges

4. Investing in immunization

What does immunization cost?

Is the investment worth making?

Who pays the bill and how?

National governments

Multilateral, bilateral, and other donors

The Global Polio Eradication Initiative

The GAVI Alliance

New financing mechanisms

The International Finance Facility for Immunisation

Advance Market Commitment

A concluding conundrum

5. The view from the future

PART 2: Diseases and their vaccines

Cholera – exploring the use of available vaccines

Diphtheria – controlled by vaccines but waiting to resurface

Haemophilus influenzae type b (Hib) – increased attention for this little known but lethal disease

Hepatitis A – paradox and potential

Hepatitis B – the first vaccine against cancer

Human papillomavirus – a second cancer vaccine

Influenza – keeping scientists guessing

Japanese encephalitis – a regional scourge, waning but still present

Measles – record progress but risk of resurgence is high

Meningococcal disease – still a deadly menace across Africa

Mumps – not always mild, not yet conquered

Pertussis – too many children not being vaccinated, too many uncounted deaths

Pneumococcal disease – many deaths from many strains, many hopes from new vaccines

Polio a tough end-game

Rabies – a terrible but vaccine-preventable death

Rotavirus – vaccines set to prevent half a million child deaths a year

Rubella – eliminating a threat to the unborn

Tetanus, neonatal and maternal – victory in sight

Tuberculosis – waiting for a better vaccine

Typhoid fever – vaccines ready and waiting

Varicella and herpes zoster – a single virus that can linger for a lifetime

Yellow fever – defusing a bomb waiting to explode

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