Gene expression and regulation 1st Edition by Jun Ma ISBN 0387332081 978-0387332086
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Product details:
ISBN 10: 0387332081
ISBN 13: 978-0387332086
Author: Jun Ma
This book offers a comprehensive look at the science of gene expression and regulation. Focusing on topics such as actions of nuclear receptors, RNA processing, and DNA methylation and imprinting, Gene Expression and Regulation is edited by a leading biologist and includes contributions by experts in the field. The focus is on scientific concepts and issues, rather than specific organisms or experimental approaches.
Table of contents:
The History
Transcription: The Never Ending Story
The Machinery
The General Transcription Machinery and Preinitiation Complex Formation
The Dynamic Association of RNA Polymerase II with Initiation, Elongation, and RNA Processing Factors during the Transcription Cycle
General Cofactors: TFIID, Mediator and USA
Chromatin and Regulation of Gene Expression
HATs and HDACs
Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
The Regulators
Transcriptional Activators and Activation Mechanisms
Transcriptional Repressors and Repression Mechanisms
STATs in Cytokine-mediated Transcriptional Regulation
Transcriptional Regulation by Smads
The Rb and E2F Families of Proteins
c-Jun: A Complex Tale of a Simple Transcription Factor
HIV Tat and the Control of Transcriptional Elongation
Post-translational Modifications of the p53 Transcription Factor
Actions of Nuclear Receptors
The Regulators
NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
Hox Genes
Nuclear Factor-kappa B’
The ATF Transcription Factors in Cellular Adaptive Responses
The Genome
Special Topics
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Jun Ma,Gene expression,expression and regulation