Sialobiology Biosynthesis Structure and Function 1st Edition by Joe Tiralongo, Ivan Martinez Duncker ISBN 978-1608053865 1608053865

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Product details: 

ISBN 10: 1608053865 

ISBN 13:  978-1608053865

Author:  Joe Tiralongo, Ivan Martinez-Duncker 

This eBook presents a summary of central aspects of sialobiology (i.e., the study of sialic acid and its relevance to biology). The importance of substitution by the sugar sialic acid and the role played by sialylated structures (eg. glycoproteins, glycolipids, glycoconjugates) in immune recognition, neural cell growth, embryogenesis and disease development including microbial pathogenesis and cancer progression, has become well-established.

Since 1995, the field of sialobiology has expanded greatly as many of the key enzymes involved in sialic acid biosynthesis, as well as the vast majority of sialic acid binding lectins involved in immune recognition, have only been cloned, characterised and structural eluciated after the publication of earlier works on the subject. This e-book also covers these recent developments. Chapters in this e-book have been contributed by eminent sialobiologists. Therefore, a book of this nature is timely and will prove to be a definitive volume with a high impact in this field for glycobiologists and cell biologists.

Table of contents: 

1. Foreword – Mark von Itzstein
2. Preface – Joe Tiralongo, Ivan Martinez-Duncker
3. List of Contributors – Joe Tiralongo, Ivan Martinez-Duncker
4. Introduction to Sialic Acid Structure, Occurrence, Biosynthesis and Function – Joe Tiralongo
5. Polysialic Acid – Chihiro Sato
6. Sialic Acid Biosynthesis in Vertebrates – Anja K. Münster-Kühnel, Stephan Hinderlich
7. CMP-Sialic Acid Transporter – Andrea Maggioni, Ivan Martinez-Duncker, Joe Tiralongo
8. Vertebrate Sialyltransferases – Anne Harduin-Lepers
9. Mammalian Sialidases – Tadashi Suzuki, Kazunori Yamaguchi
10. Bacterial Sialate O-Acetyltransferases – Martina Mühlenhoff, Anne K. Bergfeld
11. Sialic Acid Recognition, Removal and Surface Presentation: Role in Microbial Pathogenesis of Human Hosts – Christopher J. Day, Joe Tiralongo
12. Milk Sialooligosacharides: Biological Implications and Purification Strategies – Ulrike Hubl, Eduard Nekrasov
13. Gangliosides – Eduard Nekrasov, Ulrike Hubl
14. Sialic Acids and Cancer – Alexandre S. Stephens, Christopher J. Day, Joe Tiralongo
15. Synthesis of Sialic Acid-Containing Oligosaccharides and Sialylmimetics – Sadagopan Magesh, Hiromune Ando
16. Advances in Sialic Acid and Polysialic Acid Detection Methodologies – Sebastian P. Galuska
17. Metabolic Glycoengineering of Sialic Acids – Jian Du, Ruben T. Almaraz, Elaine Tan, Kevin J. Yarema
18. Index – Joe Tiralongo, Ivan Martinez-Duncker

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Tags: Joe Tiralongo, Ivan Martinez Duncker, Sialobiology Biosynthesis, Structure and Function