Microbiological Assay for Pharmaceutical Analysis A Rational Approach 1st Edition by William Hewitt ISBN 9780849318245 0849318246
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Product details:
ISBN 10: 0849318246
ISBN 13: 9780849318245
Author: William Hewitt
A user-friendly guide for the evaluation of microbiological assays, this book provides a lucid explanation of the sources of error in microbiological assay and helps analysts choose efficient assay designs that will minimize those sources of error. The author discusses microbiological assay as a branch of pharmaceutical analysis and distinguishes it from biological assay in general. He draws attention to the microbiological aspects that may not be so obvious to the chemical analyst and to the analytical aspects that may not be so obvious to the microbiologist. The book expands on the guidance given in pharmacopoeias and helps readers choose the assay design most appropriate for the purpose of their assay.
Table of contents:
1. Microbiological Assay in Perspective
2. The Agar Diffusion Assay – Its Quantitative Basis
3. The Theory and Practice of Tube Assays for Growth-Promoting Substances
4. The Theory and Practice of Tube Assays for Growth-Promoting Substances
5. What Do We Want of an Assay? How Do We Attain Our Goal?
6. General Practical Aspects of Microbiological Assays
7. Standard Reference Materials
8. Preliminary Evaluation of Data
9. Parallel-Line Assays – Some Designs and Their Evaluation
10. Slope Ratio Assays – Some Designs and Their Evaluation
11. Choice of Experimental Design
12. Concluding Thoughts
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Tags: William Hewitt, Microbiological Assay, Pharmaceutical Analysis, A Rational Approach