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(Ebook PDF) Inhaled Steroids in Asthma Optimizing Effects in the Airways 1st Edition by Robert Schleimer ISBN 9780203908532 0203908538 full chapters

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Inhaled Steroids in Asthma Optimizing Effects in the Airways 1st Edition Robert P. Schleimer Digital Instant Download

Author(s): Robert P. Schleimer
ISBN(s): 9780824705855, 0585416087
Edition: 1
File Details: PDF, 4.31 MB
Year: 2001
Language: english
SKU: EB-1650566 Categories: , Tag:

(Ebook PDF) Inhaled Steroids in Asthma Optimizing Effects in the Airways 1st Edition by Robert Schleimer-Ebook PDF Instant Download/Delivery:9780203908532, 0203908538

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Product details:

ISBN 10:0203908538

ISBN 13:9780203908532

Author: Robert P. Schleimer

This book sums up the mechanistic basis, current status, and future prospects of steroid inhalation as the cornerstone of prophylactic asthma therapy, identifying its kinetic basis-especially the essential airway selectivity-and including a historical account of inhaled glucocorticoid development. Makes connections among the underlying pharmacol
 

Table of Contents:

  • Part One: Introduction
  • 1: Drug Development of Inhaled Steroids
  • Part Two: Use of Inhaled Steroids
  • 2: How Inhaled Corticosteroids Changed Asthma Therapy
  • 3: Side Effects of Inhaled Corticosteroids
  • Part Three: Molecular Aspects of Steroid Action
  • 4: Mechanisms of Gene Regulation by the Glucocorticoid Receptor
  • 5: Relationship of Dose- and Time-Dependent Corticosteroid Responses to Receptor Turnover
  • 6: Blockade of Chemokine Production/Function as an Example of Glucocorticoid Anti-inflammatory Actio
  • 7: Newly Recognized Glucocorticoid Targets
  • Part Four: Determinants of Airway Lung selectivity
  • 8: Aerosol Delivery Devices and Airways/Lung Deposition
  • 9: Uptake, Retention, and Biotransformation of Corticosteroids in the Lung and Airways
  • 10: Systemic Disposition and Effects of Inhaled Corticosteroids
  • 11: Extrapulmonary Effects of Inhaled Corticosteroids
  • 12: Factors Involved in the Pulmonary Targeting of Inhaled Glucocorticoids
  • 13: Reversible Glucocorticoid Esterification
  • Part Five: Airway lung Selectivity of Current Inhaled Steroids
  • 14: Airway Selectivity of Current Inhaled Corticosteroids in Properly Designed Studies
  • 15: Childhood Asthma and Growth
  • 16:Evaluation and Comparison of Inhaled Steroids
  • Part Six: In Vivo Research on Airway Lung Selectivity
  • 17: The Role of Direct Assessment of Airway Inflammation in Evaluating Inhaled Glucocorticosteroid E
  • 18: Use of Exhaled Nitric Oxide as Readout for Inhaled Corticosteroid Efficacy
  • 19: Markers of Systemic Actions of Corticosteroids
  • 20: Patient Adherence to Inhaled Corticosteroid Therapy
  • Part Seven: Future Challenges
  • 21: Prospects for Developing Inhaled Steroids with Extrahepatic Metabolism
  • 22: Design and Development of a Soft Corticosteroid, Loteprednol Etabonate
  • 23: Design and Development of a Soft Corticosteroid, Loteprednol Etabonate
  • 24: Transcription Factors AP-1 and NF-кB as Targets for Development of Anti-inflammatory Drugs
  • 25: Remodeling and the Effects of Steroids in Asthma
  • 26: Inhaled Corticosteroids and the Natural History of Asthma
  • 27: Combination Therapies Using Inhaled Corticosteroids

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