Growth factors and their receptors in cancer metastasis 1st Edition by Wen Jiang, Matsumoto, Nakamura ISBN 978-0792371410 0792371410

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Product details: 

ISBN 10:  0792371410

ISBN 13: 978-0792371410

Author: Wen G. Jiang, K. Matsumoto, T. Nakamura

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our understanding of how two major groups, the group composed of initiated signals are mediated has both the bone morphogenetic proteins increased dramatically in the last fifteen (BMP) and growth and differentiation years. Firstly, the prototype of factors (GDFs), and the group formed by this still constantly growing family, was the Activins, and Nodals. The two identified and cloned (1). Secondly, the groups differ in their use of receptors for family receptors were transmembrane receptors and the identified by expression cloning from subsequent activation of the mammalian tissue culture (2-7). Thirdly, transcriptional mediators (for recent genetic screens in Drosophila reviews see (13, 14, 17)).

Table of contents: 

1. The Role of Leukemia Inhibitory Factor in Cancer and Cancer Metastasis
2. FARHAD RAVANDI AND ZEEV ESTROV
3. Interleukin-2 and Its Receptors in Human Solid Tumours: Immunobiology and Clinical Significance THERESA L. WHITESIDE, TORSTEN E. REICHERT, AND QING PING DOU.
4. Interleukin-8 and Angiogenesis TRACEY A. MARTIN.
5. The Role of Interleukin-11 in the Formation of Bone Metastases. NAOYA FUJITA AND TAKASHI TSURUO.
6. Therapeutic Potential of Adenovirus Mediated Interleukin-12 Gene Therapy for Prostate Cancer
7. SHIN EBARA, YASUTOMO NASU, TAKEFUMI SATOH, SATORU SHIMURA, CHRIS H. BANGMA, GERALD W. HULL, MARK A. MCCURDY, JIANXIANG WANG, GUANG YANG, TERRY L. TIMME, AND TIMOTHY C..
8. Fibroblast Growth Factors and Their Receptors in Metastases of Prostate and Other Urological Cancers
9. ZORAN CULIG, MARCUS V. CRONAUER, ALFRED HOBISCH, GEORG BARTSCH AND HELMUT KLOCKER.
10. Insulin-Like Growth Factor Axis Elements in Breast Cancer
11. Progression EMILIA MIRA, ROSA ANA LACALLE, CARLOS MARTÍNEZ-A. AND SANTOS MAÑES.
12. The Role of Platelet Derived Growth Factor (PDGF) and Its Receptors in Cancer and Metastasis
13. SARA WEISS FEIGELSON, CHERYL FITZER-ATTAS, LEA EISENBACH.
14. TGFẞ receptor Signaling in Cancer and Metastasis
15. MARTIN OFT.
16. VEGF-C/VEGFRS and Cancer Metastasis
17. YUTAKA YONEMURA, YOSHIO ENDOU, TAKUMA SASAKI, KAZUO SUGIYAMA, TETUMOURI YAMASHIMA, TAINA PARTANEN, KARI ALITALO.
18. HGF-c-met receptor Pathway in Tumor Invasion-Metastasis and Potential Cancer Treatment with NK4
19. KUNIO MATSUOTO AND TOSHIKAZU NAKAMURA.
20. Growth Factor Receptors and Cell Adhesion Complexes in
21. Cytoskeletal Assembly/Anchorage
22. GAYNOR DAVIES, MALCOLM D. MASON AND WEN G. JIANG
23. Index

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Tags: Wen Jiang, Matsumoto, Nakamura, Growth factors, their receptors