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Genome Analysis Current Procedures and Applications 1st Edition by Maria Poptsova ISBN 978-1908230294 1908230290

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Genome Analysis Current Procedures and Applications 1st Edition Maria S. Poptsova Digital Instant Download

Author(s): Maria S. Poptsova
ISBN(s): 9781908230683, 1908230681
Edition: 1
File Details: PDF, 12.73 MB
Year: 2014
Language: english
SKU: EB-51660594 Category: Tag:

Genome Analysis Current Procedures and Applications 1st Edition by Maria S. Poptsova  – Ebook PDF Instant Download/Delivery:  978-1908230294, 1908230290
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Product details: 

ISBN 10:   1908230290

ISBN 13: 978-1908230294

Author:  Maria S. Poptsova 

In recent years there have been tremendous achievements made in DNA sequencing technologies and corresponding innovations in data analysis and bioinformatics that have revolutionized the field of genome analysis. In this book, an impressive array of expert authors highlight and review current advances in genome analysis. This volume provides an invaluable, up-to-date and comprehensive overview of the methods currently employed for next-generation sequencing (NGS) data analysis, highlights their problems and limitations, demonstrates the applications and indicates the developing trends in various fields of genome research. The first part of the book is devoted to the methods and applications that arose from, or were significantly advanced by, NGS technologies: the identification of structural variation from DNA-seq data; whole-transcriptome analysis and discovery of small interfering RNAs (siRNAs) from RNA-seq data; motif finding in promoter regions, enhancer prediction and nucleosome sequence code discovery from ChiP-Seq data; identification of methylation patterns in cancer from MeDIP-seq data; transposon identification in NGS data; metagenomics and metatranscriptomics; NGS of viral communities; and causes and consequences of genome instabilities. The second part is devoted to the field of RNA biology with the last three chapters devoted to computational methods of RNA structure prediction including context-free grammar applications. An essential book for everyone involved in sequence data analysis, next-generation sequencing, high-throughput sequencing, RNA structure prediction, bioinformatics and genome analysis.

Table of contents: 

1. Identification of Structural Variation
Suzanne S. Sindi and Benjamin J. Raphael

2. Methods for RNA Isolation, Characterization and Sequencing (RNA-Seq)
Paul Zumbo and Christopher E. Mason

3. Transcriptome Reconstruction and Quantification from RNA Sequencing Data
Thomas J. Hardcastle

4. Identification of Small Interfering RNA from Next-generation Sequencing Data

5. Motif Discovery and Motif Finding in ChIP-Seq Data
Ivan V. Kulakovskiy and Vsevolod J. Makeev

6. Mammalian Enhancer Prediction
Dongwon Lee and Michael A. Beer

7. DNA Patterns for Nucleosome Positioning
Ilya Ioshikhes

8. Hypermethylation in Cancer
Marta Sánchez-Carbayo

9. Identification and Analysis of Transposable Elements in Genomic Sequences
Sahar Al Seesi, Serghei Mangul, Adrian Caciula, Alex Zelikovsky, and Ion Măndoiu

10. The Current State of Metagenomic Analysis
Pieter De Maayer, Angel Valverde, and Don A. Cowan

11. Metatranscriptomics

12. Inferring Viral Quasispecies Spectra from Shotgun and Amplicon Next-Generation Sequencing Reads

13. DNA Instability in Bacterial Genomes: Causes and Consequences

14. Comparative Methods for RNA Structure Prediction

15. Context-free Grammars and RNA Secondary Structure Prediction

16. Stochastic Context-free Grammars and RNA Secondary Structure Prediction
Atsushi Ogura

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Tags: Maria Poptsova, Genome Analysis, Procedures and Applications