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Drug Induced Liver Disease 2nd Edition by Neil Kaplowitz, Laurie DeLeve ISBN 0367446200 978-0367446208

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Drug Induced Liver Disease 2nd ed Edition Neil Kaplowitz Digital Instant Download

Author(s): Neil Kaplowitz, Laurie D. DeLeve
ISBN(s): 9780849398964, 0849398967
Edition: 2nd ed
File Details: PDF, 30.30 MB
Year: 2007
Language: english
SKU: EB-1368850 Category: Tags: ,

Drug Induced Liver Disease 2nd Edition by Neil Kaplowitz,  Laurie D. DeLeve – Ebook PDF Instant Download/Delivery: 0367446200, 978-0367446208
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Product details: 

ISBN 10: 0367446200 

ISBN 13: 978-0367446208

Author:  Neil Kaplowitz,  Laurie D. DeLeve

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines. This book supplies an in-depth discussion of drug-induced hepatoxicology, covering mechanisms, histopathology, management, risk factors, and patterns of drug and toxin-induced disease. It includes contributions international experts.

Table of contents: 

Part I: Mechanisms of Liver Injury

  1. Drug-Induced Liver Disease
  2. Cytochrome P450 Activation of Toxins and Hepatotoxicity
  3. Antioxidant Defense in Liver Injury: Oxidant Stress, Antioxidant Defense, and Liver Injury
  4. Hepatotoxicity Due to Mitochondrial Injury
  5. Mechanisms of Cell Death and Relevance to Drug Hepatotoxicity
  6. Significance of Hepatobiliary Transporters for Drug-Induced Liver Disease
  7. Immunological Mechanisms in Drug-Induced Liver Injury
  8. Mechanistic Role of Acyl Glucuronides
  9. Nonparenchymal Cells, Inflammatory Macrophages, and Hepatotoxicity
  10. Role of Tissue Repair in Liver Injury
  11. Genetic Susceptibility to Drug-Induced Liver Disease

Part II: Diagnosis and Management

  1. Clinicopathological Patterns of Drug-Induced Liver Disease
  2. Histopathology of Drug-Induced Liver Disease
  3. Risk Factors for Drug-Induced Liver Disease
  4. Genomics, Proteomics, and Metabolomics in the Diagnosis and Mechanisms of Drug-Induced Liver Disease
  5. Causality Assessment
  6. Management of the Patient with Drug-Induced Liver Disease

Part III: Hepatotoxicity of Specific Drugs

  1. Mechanisms of Acetaminophen-Induced Liver Disease
  2. Acetaminophen: Pathology and Clinical Presentation of Hepatotoxicity
  3. Mechanisms Underlying the Hepatotoxicity of Nonsteroidal Anti-inflammatory Drugs
  4. Nonsteroidal Anti-inflammatory Drugs and Leukotriene Receptor Antagonists: Pathology and Clinical Presentation of Hepatotoxicity
  5. Mechanism, Pathology, and Clinical Presentation of Hepatotoxicity of Anesthetic Agents
  6. Anticonvulsant Agents
  7. Hepatotoxicity of Psychotropic Drugs and Drugs of Abuse
  8. Antibacterial and Antifungal Agents
  9. Hepatotoxicity of Antituberculosis Drugs
  10. Hepatic Toxicity of Antiviral Agents
  11. Hepatotoxicity of Cardiovascular and Antidiabetic Medications
  12. Cancer Chemotherapy
  13. Hepatotoxicity of Immunomodulating Agents and the Transplant Situation
  14. Methotrexate Controversies
  15. Adverse Effects of Hormones and Hormone Antagonists

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Neil Kaplowitz,Laurie DeLeve,Drug Induced,Liver Disease