Advances in Immunology 80 1st Edition by Frank Dixon ISBN 0120224801 978-0120224807

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Product details: 

ISBN 10: 0120224801

ISBN 13:  978-0120224807

Author:  Frank J. Dixon

Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles in this volume address topics such as protein degradation and the generation of MHC class I-presented peptides, proteolysis and antigen presentation by MHC Class II molecules, cytokine memory of T-helper lymphocytes, Ig gene hypermutation, generalization of single immunological experiences by idiotypically mediated clonal connections, and aging of the immune system. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Table of contents: 

KENNETH L. ROCK, IAN A. YORK, TOMO SARIC, AND ALFRED L. GOLDBERG
I. Introduction
II. Protein Degradation

III. Antigen Presentation IV. Conclusion

Proteolysis and Antigen Presentation by MHC Class II Molecules PAULA WOLF BRYANT, ANA-MARIA LENNON-DUMÉNIL, EDDA FIEBIGER, CÉCILE LAGAUDRIÈRE-GESBERT, AND HIDDE L. PLOEGH
I. Introduction
II. Protease Activity in Antigen-Presenting Cells III. Proteolytic Digestion of li
IV. Proteolytic Control of Vesicle Biogenesis and Class II Trafficking through the Endocytic Pathway
V. The Role of li in Regulating the Proteolytic Activities of APCs
VI. Antigen Processing
VII. Concluding Remarks
Cytokine Memore of T Helper Lymphocytes
MAX LÖHNING, ANNE RICHTER, AND ANDREAS RADBRUCH
I. Introduction
II. Cytokine Signals in the Induction of T Cell Cytokine MemoreIII. Key Transcription Factors in the Induction and Maintenance of Cytokine Memory
IV. Role of the Antigen-Presenting Cell in the Induction of Cytokine Memory
V. T Cell Receptor Signals in the Induction of Cytokine Memory VI. Epigenetic Modifications of Cytokine Genes
VII. Stability and Plasticity of Cytokine Memory
VIII. Cytokine Memory as Part of T Cell Differentiation Programs IX. Cytokine Memory of Memory T Cells

JEAN-CLAUDE WEILL, BARBARA BERTOCCI, AHMAD FAILI, SAID AOUFOUCHI, STÉPHANE FREY, ANNIE DE SMET,
SÉBASTIEN STORCK, AURIEL DAHAN, FRÉDÉRIC DELBOS,
SANDRA WELLER, ERIC FLATTER, AND CLAUDE-AGNÈS REYNAUD
I. Introduction
II. Mismatch Repair
III. The “Nickase”
IV. The Role of Transcription
V. Hypermutation Is Generated by a DNA Polymerase
VI. Error-Prone DNA Polymerases
VII. More DNA Polymerases
VIII. Targeting to Non-Ig Genes
IX. AID

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